翻訳と辞書 Words near each other ・ Ibn Zaydún ・ Ibn Ziad ・ Ibn Ziad District ・ Ibn Zuhr ・ Ibn Zura ・ IBN-7 ・ Ibn-e-Imam Degree Science College ・ Ibn-e-Insha ・ Ibn-e-Qasim Bagh Stadium ・ Ibn-e-Safi ・ Ibn-i-Abhar ・ Ibn-i-Asdaq ・ IBN-Lokmat ・ Ibn-Rushd (crater) ・ Ibni Oumar Mahamat Saleh ・ IBNtxA ・ Ibnu Parna ・ Ibnu Sutowo ・ Ibnul Haider ・ Ibo ・ Ibo (Mozambique) ・ Ibo Bonilla ・ Ibo District ・ Ibo District, Hyōgo ・ Ibo loa ・ Ibo, o sangue do silêncio ・ Ibodutant ・ Ibogaine ・ Ibogamine ・ Ibogawa, Hyōgo Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク IBNtxA ： ウィキペディア英語版 IBNtxA IBNtxA is an atypical opioid analgesic drug derived from naltrexone. In animal studies it produces potent analgesic effects which are blocked by levallorphan and so appear to be μ-opioid mediated, but it fails to produce constipation or respiratory depression, and is neither rewarding or aversive in conditioned place preference protocols. These unusual properties are thought to result from agonist action at a splice variant or heterodimer of the μ-opioid receptor, rather than at the classical full length form targeted by conventional opioid drugs.〔Majumdar S, Grinnell S, Le Rouzic V, Burgman M, Polikar L, Ansonoff M, Pintar J, Pan YX, Pasternak GW. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects. ''Proceedings of the National Academy of Sciences USA''. 2011 Dec 6;108(49):19778-83. PMID 22106286〕 == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「IBNtxA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.