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INPP1
Inositol polyphosphate 1-phosphatase is an enzyme that, in humans, is encoded by the ''INPP1'' gene.〔(【引用サイトリンク】 url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3628 )〕
==Model organisms==
Model organisms have been used in the study of INPP1 function. A conditional knockout mouse line, called ''Inpp1tm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty four tests were carried out on mutant mice, and one significant abnormality was observed: a decreased susceptibility to bacterial infection.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「INPP1」の詳細全文を読む
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