翻訳と辞書 Words near each other ・ Iqqur Ipuš ・ Iqra Institute for Higher Education ・ Iqra Khalid ・ Iqra National University ・ Iqra Promotions ・ Iqra Quraishi ・ Iqra schools and colleges Sadiqbad, Pakistan ・ Iqra University ・ Iqraa TV ・ Iqraar by Chance ・ Iqram Dinzly ・ Iqrar Ahmad Khan ・ Iqrar Ul Hassan ・ IQRF ・ Iqrit ・ IQSEC1 ・ IQSEC2 ・ IQSEC3 ・ IQsoft ・ Iqta' ・ IQTELL ・ Iqtisaduna ・ IQU ・ Iquan's Party ・ IQuate ・ IQue ・ IQue (disambiguation) ・ IQue Player ・ IQuest ・ Iquiara tuiuca Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク IQSEC1 ： ウィキペディア英語版 IQSEC1 IQ motif and SEC7 domain-containing protein 1 also known as ARF-GEP100 (ADP-Ribosylation Factor - Guanine nucleotide-Exchange Protein - 100-kDa) is a protein that in humans is encoded by the ''IQSEC1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9922 )〕 ==Function== The ARF-GEP100 protein is involved in signal transduction. It is a guanine nucleotide exchange factor that promotes binding of GTP to ADP ribosylation factor protein ARF6 and to a lesser extent ARF1 and ARF5.〔 This activates the ADP-ribosylation activity of the target protein and cause it to modify its substrates. ARF-GEP100, through activation of ARF6, is therefore involved in the control of processes such as endocytosis of plasma membrane proteins, E-cadherin recycling and actin cytoskeleton remodeling. ARF-GEP100 appears particularly important in regulating cell adhesion, with reductions in the level of this protein causing enhanced spreading and attachment of cells. It is highly expressed in the prefrontal cortex, and throughout the rest of the brain, and is believed to have a role in learning and memory, having been detected as phosphorylated in a phospho screen of the PSD. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「IQSEC1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.