翻訳と辞書 Words near each other ・ Iretron ・ IReview ・ Ireviken event ・ Irevna ・ Irewe ・ Irewole ・ IREX ・ Irezumi ・ IRF ・ IRF1 ・ IRF2 ・ IRF3 ・ IRF4 ・ IRF5 ・ IRF6 ・ IRF7 ・ IRF8 ・ IRF9 ・ Irfan ・ Irfan (actor) ・ Irfan (band) ・ Irfan (disambiguation) ・ Irfan (name) ・ Irfan Abidi ・ Irfan Ahmed ・ Irfan Alam ・ Irfan Ashraf ・ Irfan Bachdim ・ Irfan Bakti Abu Salim ・ Irfan Bhatti Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク IRF7 ： ウィキペディア英語版 IRF7 Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. == Function == IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3665 )〕 The IRF7 pathway was shown to be silenced in some metastatic breast cancer cell lines, which may help the cells avoid the host immune response. Restoring IRF7 to these cell lines reduced metastases and increased host survival time in animal models. The IRF7 gene and product were shown to be defective in a patient with severe susceptibility to H1N1 influenza, while susceptibility to other viral diseases such as CMV, RSV, and parainfluenza was unaffected. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「IRF7」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.