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ITPKB
Inositol-trisphosphate 3-kinase B is an enzyme that in humans is encoded by the ''ITPKB'' gene. == Function ==
The protein encoded by this gene regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3707 )〕 Itpkb regulates immune cell function and is required for T and B cell development.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ITPKB」の詳細全文を読む
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