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Immunogenetics or immungenetics is the branch of medical research that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease. ==Origin== Its origin is usually attributed to Edward Jenner, who discovered in 1796 that cowpox, or vaccinia, induced protection against human smallpox. It took two centuries before the World Health Organization announced in 1979 that smallpox had been eradicated. The term immunogenetics is based on the two words immunology and genetics, and is defined as “a sub-category of genetics focussing on the genetic basis of the immune reaction” according to MeSH.〔NCBI/NLM, 1971〕 Genetics (based on Greek γενεά ''geneá'' "descent" and γένεσις ''génesis'' "origin") is the science researching the transfer of characteristics from one generation to the next. The genes of an organism (strands of DNA) and the transfer of genes from the parent to the child generation of an organism in the scope of possible variations are the basis of genetics. Immunology deals with the biological and biochemical basis for the body's defense against germs such as bacteria, virus and mycosis (fungal infections) as well as foreign agents such as biological toxins and environmental pollutants, and failures and malfunctions of these defence mechanisms. Apart from these external effects on the organism, there are also defence reactions regarding the body’s own cells, e.g. in the scope of the bodily reactions on cancer and the lacking reaction of a body on healthy cells in the scope of an immune-mediated disease. Hence, immunology is a sub-category of biology. The term immungenetics comprises all processes of an organism, which are on the one hand controlled and influenced by the genes of the organism, and are on the other hand significant with regard to the immunological defence reactions of the organism. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Immunogenetics」の詳細全文を読む スポンサード リンク
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