| 翻訳と辞書 |
Interferome
Interferome is an online bioinformatics database of interferon-regulated genes (IRGs). These Interferon Regulated Genes are also known as Interferon Stimulated Genes (ISGs). The database contains information on type I (IFN alpha, beta), type II (IFN gamma) and type III (IFN lambda) regulated genes and is regularly updated. It is used by the interferon and cytokine research community 〔http://www.isicr.org/〕 both as an analysis tool and an information resource. Interferons were identified as antiviral proteins more than 50 years ago. However, their involvement in immunomodulation, cell proliferation, inflammation and other homeostatic processes has been since identified. These cytokines are used as therapeutics in many diseases such as chronic viral infections, cancer and multiple sclerosis.〔http://www.cancerhelp.org.uk/help/default.asp?page=4009〕 These interferons regulate the transcription of approximately 2000 genes in an interferon subtype, dose, cell type and stimulus dependent manner. This database of interferon regulated genes is an attempt at integrating information from high-throughput experiments and molecular biology databases to gain a detailed understanding of interferon biology.
==Contents==
Interferome comprises the following data sets:
*Gene expression data of interferon regulated genes from ''Homo sapiens'', ''Mus musculus'', and ''Pan troglodytes'', manually curated from more than 30 public and inhouse microarray and proteomic datasets.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Interferome」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|