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An interolog is a conserved interaction between a pair of proteins which have interacting homologs in another organism. The term was introduced in a 2000 paper by Walhout et al.〔http://genome.cshlp.org/content/14/6/1107.full#ref-50〕 == Example == Suppose that A and B are two different interacting human proteins, and A' and B' are two different interacting dog proteins. Then the interaction between A and B is an interolog of the interaction between A' and B' if the following conditions all hold: *A is a homolog of A'. (Protein homologs have similar amino acid sequences and derive from a common ancestral sequence). *B is a homolog of B'. *A and B interact. *A' and B' interact. Thus, interologs are homologous pairs of protein interactions across different organisms. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Interolog」の詳細全文を読む スポンサード リンク
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