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Infectious salmon anemia virus
Infectious salmon anemia or anaemia (ISA) is a viral disease of Atlantic Salmon (''Salmo salar'') that affects fish farms in Canada, Norway, Scotland and Chile, causing severe losses to infected farms.〔http://www.fis.com/fis/worldnews/worldnews.aspfil=e&ndb=1&id=30796〕 The disease is listed as a non-exotic disease of the EU and is therefore watched closely by the European Community Reference Laboratory for Fish Diseases. ==Virology==
The aetiological agent of ISA is the infectious salmon anemia virus (ISAV). ISAV, a RNA virus, is the only species in the genus "Isavirus" which is in the family Orthomyxoviridae and therefore related to the influenza viruses. The genome encodes at least 10 proteins.〔Tello M, Vergara F, Spencer E (2013) "Genomic adaptation of the ISA virus to ''Salmo salar'' codon usage". ''Virol J'' 10(1):223 〕 There are several distinct strains of the virus. The most common are a European strain and a North American strain.〔()〕
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