翻訳と辞書 Words near each other ・ Jyothi Krishna (cricketer) ・ Jyothi Lakshmi ・ Jyothi Lakshmi (film) ・ Jyothi Nagar ・ Jyothi Nilayam School, Thiruvananthapuram ・ Jyothi Raj ・ Jyothi Rana ・ Jyothi Surekha Vennam ・ Jyothika ・ Jyothirgamaya ・ Jyothirgamaya foundation ・ Jyothirmayi ・ Jyothishmathi College of Engineering and Technology ・ Jyothy Kendriya Vidyalaya ・ Jyothy Laboratories ・ JWH-098 ・ JWH-116 ・ JWH-120 ・ JWH-122 ・ JWH-133 ・ JWH-147 ・ JWH-148 ・ JWH-149 ・ JWH-161 ・ JWH-164 ・ JWH-167 ・ JWH-175 ・ JWH-176 ・ JWH-184 ・ JWH-185 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク JWH-098 ： ウィキペディア英語版 JWH-098 JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081, but has markedly different affinity for the CB1 and CB2 receptors. While JWH-081 is around 10x selective for CB1 over CB2, in JWH-098 this is reversed, and it is around 4 times weaker than JWH-081 at CB1 while being six times more potent at CB2, giving it a slight selectivity for CB2 overall. This makes JWH-098 a good example of how methylation of the indole 2-position in the naphthoylindole series tends to increase CB2 affinity, but often at the expense of CB1 binding.〔Huffman JW, ''et al.'' Structure–activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. ''Bioorganic and Medicinal Chemistry''. 2005; 13:89-112. PMID 15582455〕 JWH-098 is illegal in Russia, Sweden,〔(Svensk författningssamling )〕 and the UK,〔(The Misuse of Drugs Act 1971 (Amendment) Order 2009 )〕 although it is unclear whether it has any history of human use. ==See also== * JWH-007 * JWH-081 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「JWH-098」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.