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Juglone : ウィキペディア英語版
Juglone

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Juglone, also called 5-hydroxy-1,4-naphthalenedione (IUPAC) is an organic compound with the molecular formula C10H6O3. In the food industry, juglone is also known as C.I. Natural Brown 7 and C.I. 75500. It is insoluble in benzene but soluble in dioxane, from which it crystallizes as yellow needles.〔 It is an isomer of lawsone, which is the staining compound in the henna leaf.
Juglone occurs naturally in the leaves, roots, husks, fruit (the epicarp), and bark of plants in the Juglandaceae family, particularly the black walnut (''Juglans nigra''), and is toxic or growth-stunting to many types of plants.〔(Juglone toxicity )〕 It is sometimes used as a herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.
==History==
The harmful effects of walnut trees on other plants have been observed for at least two millennia. The ancient civilizations of Greece and Rome used the walnut for its cytotoxic properties as did residents of the American South for easily gathering fish when they threw cut husks into the water with the fish.〔Soderquist, C.J. Juglone and Allelopathy. ''J. Chem. Educ''. 1973, 50, 782-783. 〕 However, juglone was not isolated until the 1850s. Two men, A. Vogel Jr. and C. Reischauer, were able to isolate the compound from the walnut tree in 1851. The compound was known as nucin at that time. Juglone was then synthesized and characterized for the first time in 1887 by A. Bernthsen and A. Semper. It was not until 1928 the compound was identified and confirmed to be toxic to other plants by E.F. Davis.
The use of walnut tree has historically been used within the field of traditional medicine. In America during the early 1900s, doctors prescribed juglone for the treatment of various skin diseases.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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