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Juncusol
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Juncusol : ウィキペディア英語版
Juncusol

Juncusol is a 9,10-dihydrophrenathrene found in ''Juncus'' species such as ''J. acutus'',〔Phenanthrenoids from Juncus acutus L., New Natural Lipopolysaccharide-Inducible Nitric Oxide Synthase Inhibitors. Fathi Abdelmohsen Abdelhalim Behery, Zain Elabdin Metwally Naeem, Galal Taha Maatooq, Mohamed Mahmoud Abdelfattah Amer, Zhi-Hong Wen, Jyh-Horng Sheu, Atallah Fouad Ahmed, Chemical and Pharmaceutical Bulletin, 2007, Vol. 55, No. 8, pages 1264-1266, 〕 ''J. effusus''〔Bhattacharyya,Experientia,36,(1980),27〕〔Shima,Phytochem.,30,(1991),3149〕 or ''J. roemerianus''.〔Antimicrobial activity of juncusol, a novel 9-10-dihydrophenanthrene from the marsh plant Juncus roemerianus. Kirit D. Chapatwala, Armando A. de la Cruz and D.Howard Miles, Life Sciences, 9 November 1981, Volume 29, Issue 19, Pages 1997–2001, 〕〔The structure of juncusol. A novel cytotoxic dihydrophenanthrene from the Estuarine marsh plant Juncus roemerianus. D H Miles, J Bhattacharyya, N V Mody, J L Atwood, S Black and P A Hedin, Journal of the American Chemical Society, February 1977, volume 99, issue 2, pages 618-620, 〕
It can also be synthetized.〔Total synthesis of juncusol. Edward McDonald and Roger T. Martin, Tetrahedron Letters, 1978, Volume 19, Issue 47, Pages 4723–4726, 〕〔Regiospecific total synthesis of juncusol. Dale L. Boger and Michael D. Mullican, J. Org. Chem., 1984, volume 49, issue 21, pages 4045–4050, 〕〔A novel synthesis of juncusol. Peter A. Jacobi and Wanjun Zheng, Tetrahedron Letters, 4 March 1991, Volume 32, Issue 10, Pages 1279–1282, 〕
This compound shows antimicrobial activity against ''Bacillus subtilis'' and ''Staphylococcus aureus''.〔 It also has a toxic effect on estuarine fish and shrimp.〔Toxic effects of juncusol a marsh plant phenolic extract on estuarine fish and shrimp. Chapatwala K.D, Life Sciences, 1982, volume 30, issue 21, pages 1805-1810, 〕
== References ==


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