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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク KCNE2 ： ウィキペディア英語版 KCNE2 Potassium voltage-gated channel subfamily E member 2 also known as MinK-related peptide 1 (MiRP1) is a protein that in humans is encoded by the ''KCNE2'' gene. MiRP1 is a voltage-gated potassium channel accessory subunit (beta subunit) associated with Long QT syndrome.〔 KCNE2 (MiRP1) is a ubiquitously expressed ion channel regulatory subunit that, because of this and its ability to regulate multiple different ion channels, exerts considerable influence on a number of cell types and tissues.〔 Human KCNE2 is a member of the five-strong family of human KCNE genes. KCNE proteins contain a single membrane-spanning region, extracellular N-terminal and intracellular C-terminal. KCNE proteins have been widely studied for their roles in the heart and in genetic predisposition to inherited cardiac arrhythmias. More recently, roles for KCNE proteins in a variety of non-cardiac tissues have also been explored. == Discovery == Steve Goldstein (then at Yale University) used a BLAST search strategy, focusing on KCNE1 sequence stretches known to be important for function, to identify related expressed sequence tags (ESTs) in the NCBI database. Using sequences from these ESTs, KCNE2, 3 and 4 were cloned.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「KCNE2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.