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KCNQ2 : ウィキペディア英語版
KvLQT2

Kv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2.
It is associated with benign familial neonatal epilepsy.

==Ligands==


* ICA-069673: channel opener at KCNQ2/Q3, 20-fold selective over KCNQ3/Q5, no measurable activity against a panel of cardiac ion channels (hERG, Nav1.5, L type channels, and KCNQ1) and no activity on GABAA gated channels at 10 μM. A range of related benzamides exhibited activity, of which compound number 40 is shown here.〔Amato G, JMC Lett 2011, 481, 〕
* ML252: channel inhibitor, IC50 = 70nM.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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