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Words near each other
・ KDLM
・ KDLO
・ KDLO-FM
・ KDLP
・ KDLP-LP
・ KDLR
・ KDLS
・ KDLS (AM)
・ KDLS-FM
・ KDLT tower
・ KDLT-TV
・ KDLW
・ KDLX
・ KDLY
・ KDM
KDM1A
・ KDM1B
・ KDM2A
・ KDM2B
・ KDM3B
・ KDM4A
・ KDM4B
・ KDM4C
・ KDM4D
・ KDM5A
・ KDM5C
・ KDM5D
・ KDMA
・ KDMC
・ KDMC-LP


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KDM1A : ウィキペディア英語版
KDM1A

Lysine-specific histone demethylase 1A (KDM1A) also known as lysine (K)-specific demethylase 1A (LSD1) is a protein in humans that is encoded by the KDM1A gene. LSD1 is a flavin-dependent monoamine oxidase, which can demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9 (H3K4 and H3K9). This enzyme can have roles critical in embryogenesis and tissue-specific differentiation, as well as oocyte growth. KDM1A was the first demethylase to be discovered and thus it has been studied most extensively.
== Structure ==

This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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