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・ KIAA0922
・ KIAA0999
・ KIAA1012
・ KIAA1109
・ KIAA1166
・ KIAA1199
・ KIAA1219
・ KIAA1267
・ KIAA1279
・ KIAA1333
・ KIAA1377
・ KIAA1524
・ KIAA1530
・ KIAA1539
・ KIAA1683
KIAA1704
・ KIAA1797
・ KIAA1826
・ KIAA1841
・ KIAA1949
・ KIAA1958
・ KIAA1967
・ Kiaabad
・ Kiab
・ Kiab Sar
・ Kiaban
・ Kiabonyoru primary school
・ KIAC
・ KIAD
・ Kiadeh, Mazandaran


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KIAA1704 : ウィキペディア英語版
KIAA1704

KIAA1704, also known as LSR7 (lipopolysaccharide-specific response protein 7), is a protein that in humans is encoded by the GPALPP1 (GPALPP motifs containing 1) gene. The function of KIAA1704 is not yet well understood. KIAA1704 contains one domain of unknown function, DUF3752. The protein contains a conserved, uncharged, repeated motif GPALPP(GF) near the N terminus and an unusual, conserved, mixed charge throughout (alternating readily between positive and negative charges). It is predicted to be localized to the nucleus.
== Clinical significance ==

KIAA1704 has at least a 5 fold expression loss associated with mantle cell lymphoma.

In a second study, researchers used a linkage disequilibrium mapping study of locus 13q13-14 to investigate potential susceptibility for autism over a 1.5 Mb linkage peak, including KIAA1704. A single marker PDTPhase analysis was performed for four SNPs for KIAA1704; however, none of the SNPs were statistically significant in associating the marker with the loci.
An expression study found that KIAA1704 is significantly up-regulated in U937 cells (macrophage-like human cell line) when treated with nicotine.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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