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Protein KIAA1958 is a protein that in humans is encoded by the KIAA1958 gene.〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/nuccore/NM_133465.2 )〕 Orthologs of KIAA1958 go as far back in evolution to chordates, although, it is closer in homology to primates than any other orthologs. KIAA1958 has no known paralogs. == Gene == KIAA1958 is located on the long arm of chromosome 9 (9.q32) in humans on the plus strand from 115249248 to 115427597.〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&c=Gene&l=KIAA1958 )〕 Its mRNA has 2683 bp.〔 The gene has these neighbors on chromosome 9: HSDL2: Hydroxysteroid dehydrogenase-like protein 2 plays a role in nucleotide binding, oxidoreductase activity, and sterol binding.〔(【引用サイトリンク】url=http://www.uniprot.org/uniprot/Q6YN16#section_comments )〕 C9orf147: Chromosome 9 open reading frame 147 has an unknown function.〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?exdb=AceView&db=human&term=C9orf147&submit=Go )〕 C9orf80: Chromosome 9 open reading frame 80 is a component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell cycle checkpoint activation, recombinational repair and maintenance of genomic stability.〔(【引用サイトリンク】url=http://www.uniprot.org/uniprot/Q9NRY2#section_comments )〕 SNX30: Sorting nexin-30 may be linked to phosphatidylinositol binding.〔(【引用サイトリンク】url=http://www.uniprot.org/uniprot/Q5VWJ9#section_comments )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「KIAA1958」の詳細全文を読む スポンサード リンク
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