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KIRREL3 : ウィキペディア英語版
KIRREL3

Kin of IRRE-like protein 3 (KIRREL3) also known as kin of irregular chiasm-like protein 3 or nephrin-like protein 2 (NEPH2) is a protein that in humans is encoded by the ''KIRREL3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84623 )
NEPH2 is a member of the nephrin-like protein family of transmembrane proteins, which includes NEPH1 (KIRREL) and NEPH3 (KIRREL2). The nephrin-like proteins can interact with nephrin and CASK.
== Function ==
NEPH2 has been implicated in synapse formation. Disruption of KIRREL3 gene function had been associated with abnormal brain function.
NEPH1 and NEPH2 are involved in the blood filtration function of the kidney and are located in the slit diaphragm.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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