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Knemometry Knemometry (Greek η κνημη the lower leg) denotes a technical device for measuring the distance between knee and heel of a sitting child or adolescent. Knemometric measurements show a measurement error of less than 160 µm (0.16 mm) and enable illustrating growth at intervals of few weeks (short-term growth). ==The device==
Ignaz Maria Valk developed this technique in 1983 in Nijmegen/Netherlands.〔Valk, I.M., Langhout Chabloz, A.M.E., Smals, A.G.H., Kloppenborg, P.W.C., Cassorla, F.G. & Schutte, E.A.S.T. (1983a) Accurate measurement of the lower leg length and the ulnar length and its application in short term growth measurements. Growth 47:53-66〕 It is being practiced since and used for basic research in growth and the treatment of growth disorders.〔Hermanussen M, Geiger-Benoit, K, Sippell WG (1985) Catch-up growth following transfer from three times weekly im to daily sc administration of hGH in GH deficient patients, monitored by knemometry. Acta Endocrinol 109:163-168〕〔Wolthers OD. Methodology and implications of knemometry in growth assessment of inhaled glucocorticoids. Pediatr Allergy Immunol. 2009 May 2. (ahead of print )〕 Hermanussen introduced the mini-knemometer for accurate growth measurements of prematures and newborn infants.〔Hermanussen M., and Seele K., 1997, Mini-knemometry: an accurate technique for lower leg length measurements in early childhood. Annals of Human Biology, 24, 307-313〕 Mini-knemometry determines the lower leg length with an accuracy of less than 100 µm (0.1 mm). This enables substantiating growth within 24 hours. In an animal model, the technique was used to investigate the effects of steroids and growth hormone on short-term growth.〔Hermanussen M., Rol de Lama M., Tresguerres J.A.F., Grasedyck L., and Burmeister J., 1998, Short term growth: evidence for chaotic series of mini growth spurts in rat growth. Physiology and Behavior, 64, 7-13〕 These studies were an important prerequisite for improving growth therapies.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Knemometry」の詳細全文を読む
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