翻訳と辞書
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・ L-1 Visa Reform Act of 2004
・ L-11 76.2 mm tank gun
・ L-13 Light Industrial Workshop
・ L-160
・ L-165041
・ L-2 visa
・ L-2-amino-4-chloropent-4-enoate dehydrochlorinase
・ L-2-hydroxycarboxylate dehydrogenase (NAD+)
・ L-3 Aviation Recorders
・ L-3 Communication Combat Propulsion Systems
・ L-3 Communications
・ L-3 Flight International Aviation
・ L-3 Network Security
・ L-3 SmartDeck
・ L-3-cyanoalanine synthase
L-368,899
・ L-371,257
・ L-655,708
・ L-687,384
・ L-694247
・ L-733,060
・ L-741,626
・ L-745,870
・ L-759,633
・ L-759,656
・ L-765,314
・ L-838,417
・ L-ACOUSTICS
・ L-allo-threonine aldolase
・ L-amino-acid alpha-ligase


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L-368,899 : ウィキペディア英語版
L-368,899

L-368,899 is a drug used in scientific research which acts as a selective antagonist of the oxytocin receptor, with good selectivity over the related vasopressin receptors. Unlike related drugs such as the peripherally selective L-371,257, the oral bioavailabity is high and the brain penetration of L-368,899 is rapid, with selective accumulation in areas of the limbic system. This makes it a useful tool for investigating the centrally mediated roles of oxytocin, such as in social behaviour and pair bonding, and studies in primates have shown L-368,899 to reduce a number of behaviours such as food sharing, sexual activity and caring for infants, demonstrating the importance of oxytocinergic signalling in mediating these important social behaviours.
==See also==

* Atosiban
* Barusiban
* Epelsiban
* L-371,257
* Retosiban

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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