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Droxidopa
Droxidopa (INN; trade name Northera; also known as L-DOPS, L-''threo''-dihydroxyphenylserine, L-''threo''-DOPS and SM-5688) is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline). Unlike norepinephrine, droxidopa is capable of crossing the protective blood–brain barrier (BBB).〔 ==Indications==
* Neurogenic orthostatic hypotension (NOH) dopamine beta hydrolase deficiency, as well as NOH associated with multiple system atrophy (MSA), familial amyloid polyneuropathy (FAP), pure autonomic failure (PAF), and Parkinson's disease (PD). * Intradialytic hypotension (IDH) or hemodialysis-induced hypotension. * Freezing of gait in Parkinson's disease (off-label)
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