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Glutamic acid
|Section2= |Section7= }} Glutamic acid (abbreviated as Glu or E) is one of the 20-23 proteinogenic amino acids, and its codons are GAA and GAG. It is non-essential. In neuroscience, its carboxylate anion glutamate is an important excitatory neurotransmitter that plays the principal role in neural activation. == Chemistry == The side chain carboxylic acid functional group has a pKa of 4.1 and therefore exists almost entirely in its negatively charged deprotonated carboxylate form at pH values greater than 4.1; therefore, it is negatively charged at physiological pH ranging from 7.35 to 7.45.
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