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LDHA : ウィキペディア英語版
LDHA

Lactate dehydrogenase A, also known as LDHA, is an enzyme which in humans is encoded by the ''LDHA'' gene.
== Function ==
Lactate dehydrogenase A catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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