翻訳と辞書 Words near each other ・ LM-49 ・ LM-57 ・ LM-68M ・ LM-700 ・ LM.C (Japanese band) ・ LM13700 ・ LM317 ・ LM358 ・ LM386 ・ LM3875 ・ LM3914 ・ LM3LABS ・ LMA ・ LMA Manager ・ LMAB-Group ・ LMAN1 ・ LMAN2 ・ LMAN2L ・ LMAX Exchange ・ LMB ・ LMB Hotel ・ Lmbatavank ・ LMBO ・ LMBR1 ・ LMBR1L ・ LMBRD1 ・ LMC ・ LMC (British band) ・ LMC N49 ・ LMC195-1 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク LMAN1 ： ウィキペディア英語版 LMAN1 Protein ERGIC-53 also known as ER-Golgi intermediate compartment 53 kDa protein or lectin mannose-binding 1 is a protein that in humans is encoded by the ''LMAN1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3998 )〕 == Function == ERGIC-53 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. Also named LMAN1, the protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined deficiency of factor V-factor VIII, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.〔 MCFD2 is the second gene that leads to combined deficiency of factor V-factor VIII. ERGIC-53 and MCFD2 form a protein complex and serve as a cargo receptor to transport FV and FVIII from the ER to the Golgi body.ウィキペディア（Wikipedia）』 ■ウィキペディアで「LMAN1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.