翻訳と辞書
Words near each other
・ LRPu
・ LRR
・ LRRC (Luddite Rural Recording Cooperative)
・ LRRC16A
・ LRRC17
・ LRRC23
・ LRRC37A
・ LRRC39
・ LRRC3B
・ LRRC4
・ LRRC40
・ LRRC41
・ LRRC48
・ LRRC50
・ LRRC57
LRRC7
・ LRRC8A
・ LRRC8D
・ LRRC8E
・ LRRFIP1
・ LRRK1
・ LRRK2
・ LRRN1
・ LRRN2
・ LRRN3
・ Lrrr
・ Lrrreconcilable Ndndifferences
・ LRRTM1
・ LRS
・ LRS (band)


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LRRC7 : ウィキペディア英語版
LRRC7

Leucine rich repeat containing 7 also known as LRRC7, Densin-180, or LAP1 is a protein which in humans is encoded by the ''LRRC7'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57554 )
== Structure ==

Found to be densely associated to the postsynaptic density (PSD), it has been characterised as a 188 kDa (originally thought to be 180 kDa, hence nomenclature), 1495 residues long, brain-specific protein containing 16 leucine-rich repeats (LRRs) within the 500 N-terminal residues, and one Psd95/Discs large/Zona occludens (PDZ) domain within the 200 C-terminal residues. Originally postulated to have an apparent transmembrane domain, it has now been shown that the protein has numerous phosphorylation sites both N- and C-term of this domain, and that protein is therefore cytoplasmic; palmitoylation is thought to occur near the N-terminus of the protein which would account for localisation of the protein at the PSD.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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