翻訳と辞書 ・ Lyaskovo, Dobrich Province
・ Lyaskovo, Kardzhali Province
・ Lyate ion
・ Lyati Bindraseni
・ Ly Jonaitis
・ Ly Kim Leang
・ Ly line
・ Ly Son
・ Ly Thai Hung
・ Ly Thuch
・ Ly Tong
・ LY-215,840
・ LY-2183240
・ LY-235,959
・ LY-255582
・ LY-272,015
・ LY-293284
・ LY-2940094
・ LY-307,452
・ LY-310762
・ LY-320,135
・ LY-334370
・ LY-341,495
・ LY-344,545
・ LY-367,265
・ LY-379,268
・ LY-404,039
・ LY-404,187
・ LY-487,379
・ LY-503,430
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LY-272,015
LY-272,015 is a beta-carboline derivative drug developed by Eli Lilly, which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor. It has anti-hypertensive effects in animal models,〔Watts SW, Fink GD. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. ''American Journal of Physiology''. 1999 Mar;276(3 Pt 2):H944-52. PMID 10070078〕〔Russell A, Banes A, Berlin H, Fink GD, Watts SW. 5-Hydroxytryptamine(2B) receptor function is enhanced in the N(omega)-nitro-L-arginine hypertensive rat. ''Journal of Pharmacology and Experimental Therapeutics''. 2002 Oct;303(1):179-87. PMID 12235249〕 and is also used in research into the other functions of the 5-HT2B receptor.〔Günther S, Maroteaux L, Schwarzacher SW. Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro. ''Journal of Neurobiology''. 2006 Aug;66(9):949-61. PMID 16758492〕
== References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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