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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lactoferricin ： ウィキペディア英語版 Lactoferricin Lactoferricin is an amphipathic, cationic peptide with anti-microbial〔Wakabayashi H, Takase M, Tomita M. (Lactoferricin derived from milk protein lactoferrin. ) Curr Pharm Des. 2003;9(16):1277-87.〕 and anti-cancer〔Eliassen LT, Berge G, Sveinbjornsson B, Svendsen JS, Vorland LH, Rekdal O. (Evidence for a direct antitumor mechanism of action of Bovine lactoferricin ). Anticancer Res. 2002 Sep-Oct;22(5):2703-10.〕 properties. It can be generated by the pepsin-mediated digestion of lactoferrin. Lactoferricin is the most studied AMP derived from milk protein. The complete sequence of lactoferricin corresponds to lactoferrin fragment 17-41 (FKCRRWQWRM KKLGAPSITCVRRAF; (LFB0084 )) and sequences from within this fragment are also antimicrobial. The MilkAMP database contains a total of 111 peptides (natural, synthetic and modified) comprising or derived from the complete lactoferricin.〔Jérémie Théolier, Ismail Fliss, Julie Jean, Riadh Hammami〕 In humans, lactoferricin corresponds to lactoferrin fragment 1-47 but consists of two subunits, namely fragments 1-11 and 12-47 ((LFH0009 )), connected by a disulfide bridge. ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lactoferricin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.