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・ Lactocepin
・ Lactocillin
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・ Lactococcus garvieae
・ Lactococcus lactis
・ Lactococcus piscium
・ Lactocollybia
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Lactonase
・ Lactone
・ Lactonitrile
・ Lactoperoxidase
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・ Lactoria
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・ Lactoris
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・ Lactose intolerance
・ Lactose permease
・ Lactose synthase


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Lactonase : ウィキペディア英語版
Lactonase

Lactonase (also acyl-homoserine lactonase) is a metalloenzyme, produced by certain species of bacteria, which targets and inactivates acylated homoserine lactones (AHLs).
Many species of Proteobacteria from the alpha, beta and gamma classes have been shown to produce acylated homoserine lactones, which are small hormone-like molecules commonly used as communication signals between bacterial cells in a population to regulate certain gene expression and phenotypic behaviours. This type of gene regulation is known as quorum sensing.
== Enzyme mechanism ==
Lactonase hydrolyzes the ester bond of the homoserine lactone ring of acylated homoserine lactones. In hydrolysing the lactone bond, lactonase prevents these signaling molecules from binding to their target transcriptional regulators, thus inhibiting quorum sensing.


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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