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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lactotripeptides ： ウィキペディア英語版 Lactotripeptides Lactotripeptides are two naturally occurring milk peptides: Isoleucine-Proline-Proline (IPP) and Valine-Proline-Proline (VPP). These lactotripeptides are derived from casein, which is a milk protein also found in dairy products. Although most normal dairy products contain lactotripeptides, they are inactive within the original milk proteins. Dairy peptides can be effectively released through enzymatic predigestion – a process by which milk protein is enzymatically broken down into smaller pieces. Some clinical studies have suggested that these lactotripeptides help promote healthy blood pressure levels as part of a healthy diet and lifestyle.〔Hirata H, Nakamura Y, Yada H, Moriguchi S, Kajimoto O, Takahashi T. (Clinical Effects of New Sour Milk Drink in Mild or Moderate Hypertensive Subjects ).J New Rem & Clin 2002;51:61-9.〕 However, other clinical trials have seen no effects from these compounds.〔Usinger L, Reimer C, Ibsen H. Fermented milk for hypertension. Cochrane Database of Systematic Reviews 2012, Issue 4. Art. No.: CD008118. DOI: 10.1002/14651858.CD008118.pub2.〕 == Proposed mechanism == Dairy peptides are proposed to inhibit the activity of the angiotensin-converting enzyme (ACE). ACE is part of the renin-angiotensin system — a natural mechanism that helps regulate blood pressure in the body. In certain individuals, the renin-angiotensin system can become overactive, often due to stress, an unhealthy diet, and/or unhealthy lifestyle. Under such conditions, ACE becomes overactive and converts more angiotensin I into angiotensin II. Angiotensin II causes blood vessels to constrict, and so increases blood pressure, which has potential to lead to hypertension. But, when ACE activity is inhibited, the formation of angiotensin II is reduced. This then helps the blood vessels to relax and expand back to a normal healthy state, so blood pressure is lowered. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lactotripeptides」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.