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Latrunculin
The latrunculins are a family of natural products and toxins produced by certain sponges, including genus ''Latrunculia'' and ''Negombata'', whence the name is derived. It binds actin monomers near the nucleotide binding cleft with 1:1 stoichiometry and prevents them from polymerizing. Administered ''in vivo'', this effect results in disruption of the actin filaments of the cytoskeleton. This property has been used to great effect in the discovery of cadherin distribution regulation. ==References==
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抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Latrunculin」の詳細全文を読む
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