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Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor. ==Medical use== Rheumatoid arthritis and psoriatic arthritis are the only indications that have received regulatory approval.〔 Clinical studies regarding the following diseases have been conducted:〔http://clinicaltrials.gov/ct2/results?term=Leflunomide〕
* Polyoma BK Virus Nephropathy * Kimura's disease * Systemic lupus erythematosus * Felty's syndrome * Takayasu arteritis * Granulomatosis with polyangiitis〔 * Ankylosing spondylitis * Crohn's disease * Sarcoidosis * Uveitis * Still's disease * Prostate cancer * Pemphigoid * Prevention of organ transplant rejection
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Leflunomide」の詳細全文を読む
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