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A leukoerythroblastic (or leucoerythroblastic) anemia is any anemic condition resulting from space-occupying lesions in the bone marrow; the circulating blood contains immature cells of the granulocytic series and nucleated red blood cells, frequently in numbers that are disproportionately large in relation to the degree of anemia. picture on blood film can be the bone marrow response to any irritation including marrow infiltration (immature red cells ). Marrow infiltrative disorders include myelomas, malignancy, myelofibrosis, Gaucher’s disease etc. It can also occur as a response to severe critical illness, such as trauma, septicaemia, massive haemolysis, or severe megaloblastic anaemia. Leukoerthyroblastic change refers to the presence of nucleated red blood cells and primitive white blood cells. Seen in bone marrow failure, myelofibrosis and extramedullary haematopoiesis. Features of leucoerythroblastic anaemia include: * normocytic normochromic anaemia with numerous poikilocytes * normoblasts (nucleated red cells) * low-grade reticulocytosis (2-5%) * circulating immature white cells, generally myelocytes and promyelocytes * thrombocytopenia is more common than thrombocythemia 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Leucoerythroblastic」の詳細全文を読む スポンサード リンク
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