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Levocabastine : ウィキペディア英語版 | Levocabastine
Levocabastine is a selective second-generation H1-receptor antagonist which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis.〔Pipkorn U, Bende M, Hedner J, Hedner T., A double-blind evaluation of topical levocabastine, a new specific H1 antagonist in patients with allergic conjunctivitis. ''Allergy''. 1985 Oct;40(7):491-6.〕 As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS2, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor. The pharmaceutical drug Bilina is a combination of Levocabastine, Benzalkonium chloride, and other components and is typically used in a 0.5 mg/ml suspension as eye-drops, dispensed in 4ml bottles for the treatment of allergic conjunctivitis or similar allergic ocular conditions.〔(【引用サイトリンク】website=http://www.vademecum.es/principios-activos-levocabastina+oftalmica-s01gx02 )〕 == References ==
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