翻訳と辞書 Words near each other ・ Lomellina ・ Lomellini Ewer and Basin ・ Lomello ・ Lomelo ・ Lomemus sculpturatus ・ Lomen Company ・ Lomen stave church ・ Loment ・ Lomer Brisson ・ Lomer Gouin ・ Lomerizine ・ Lomer–Cottrell junction ・ Lomes ・ Lometa Independent School District ・ Lometa, Texas ・ Lometraline ・ Lomets ・ Lomevactone ・ Lomfjorden ・ Lomfjordhalvøya ・ Lomi ・ Lomi (disambiguation) ・ Lomi's blind legless skink ・ Lomi-lomi salmon ・ Lomidze ・ Lomilomi ・ Lomilomi massage ・ Lomilysis ・ Lomin ・ Lominchar Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lometraline ： ウィキペディア英語版 Lometraline Lometraline (INN; CP-14,368) is a drug which is an aminotetralin derivative. A structural modification of the investigative neuroleptic pinoxepin, lometraline was originally patented by Pfizer as an antipsychotic, tranquilizer, and antiparkinsonian agent (likely as an anticholinergic). However, it was instead later studied as a potential antidepressant and/or anxiolytic agent, but clinical studies revealed no psychoactivity at the doses used and further investigation was suspended.〔 However, further experimental modifications of the chemical structure of lometraline directly resulted in the discovery of tametraline, a potent inhibitor of the reuptake of dopamine and norepinephrine, which in turn led to the discovery of the now widely popular antidepressant sertraline, which, remarkably, acts contrarily as a selective serotonin reuptake inhibitor (SSRI). == See also == * Sertraline * Tametraline 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lometraline」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.