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Loratadine
Loratadine (INN) is a second-generation peripheral histamine H1-receptors blocker〔 used to treat allergies. In structure, it is closely related to tricyclic antidepressants, such as imipramine, and is distantly related to the atypical antipsychotic quetiapine.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic drug and is marketed for its nonsedating properties. Loratadine is marketed by Schering-Plough under several trade names (e.g., Claritin) and also by Shionogi in Japan. It is manufactured by Pfizer〔(【引用サイトリンク】publisher=Pfizer Inc. )〕 among others. There is a version named combined with pseudoephedrine, a decongestant; known as pseudoephedrine/loratadine.
== Medical uses ==
Loratadine is indicated for the symptomatic relief of allergy such as hay fever (allergic rhinitis), urticaria (hives), chronic idiopathic urticaria, and other skin allergies. For allergic rhinitis (hay fever), loratadine is effective for both nasal and eye symptoms: sneezing, runny nose, itchy or burning eyes. Loratadine could be also used to treat mild to moderate pain from headaches.
Similarly to cetirizine, loratadine attenuates the itching associated with Kimura's disease.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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