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Lumivascular
Lumivascular refers to a procedure in which an interventional catheter with real time intravascular light (lumi) imaging capabilities is inserted percutaneously into a blood vessel (vascular) for the treatment of vascular disease with the goal of minimizing disruption to the native blood vessel.
==Potential Advantages==
Endovascular therapies have advanced to an improved approach called lumivascular. As opposed to the endovascular approach, which solely relies on the use of fluoroscopy, a lumivascular approach involves the use of light to achieve intravascular imaging. The provision of visibility into the vessel allows the physician user the opportunity to guide, orient, and protect the viability of the vessel structures while navigating and treating diseased arteries. Advantages of lumivascular include the potential to reduce harmful radiation exposure to the patient and the physician, and efficient and safe crossing of CTO's.〔Schwindt A, Reimers B, Scheinert D, Selmon M, Pigott JP, George JC, Robertson G, Janzer S, McDaniel HB, Shrikhande GV, Torsello G, Schaefers J, Saccà S, Versaci F. Crossing chronic total occlusions with the Ocelot system: the initial European experience. EuroIntervention. 2013 Jul 9. PMID 23838387〕
Adam et al. demonstrate that endovascular therapies carry less cost and associated complications when compared to surgery. Likewise, they are a safe alternative for non-viable surgical candidates as a result of their co-morbidities, lack of suitable target vessels, or poor venous conduits.〔Adam DJ, Beard JD, Cleveland T. et al. BASIL trial participants. Bypass versus angioplasty in severe ischemia of the leg (BASIL): multicenter, randomized controlled trial. ''Lancet''. 2005; 336:1925-1934.〕 A lumivascular approach allows physicians to remain within the true lumen. Intraluminal crossing may have the benefit of reducing reactive inflammatory species associated with medial and adventitial disruption, while enabling a wide array of therapeutic options including angioplasty, stenting and atherectomy.〔Krishnan, P, et al. Histopathologic evidence of adventitial cuts predicts restenosis after directional atherectomy of lower extremity peripheral arterial disease: results from a randomized, open label, investigator-initiated trial comparing intravascular ultrasound-guided atherectomy to angiography guided atherectomy in peripheral vascular interventions for TASC's A, B lesions (utopia) pilot study. E2083 JACC march 27, 2012 volume 59, issue 13〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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