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Lyme disease microbiology : ウィキペディア英語版 | Lyme disease microbiology
Lyme disease, or borreliosis, is caused by spirochetal bacteria from the genus ''Borrelia'', which has at least 37 known species, 12 of which are Lyme related, and an unknown number of genomic strains. ''Borrelia'' species known to cause Lyme disease are collectively known as ''Borrelia burgdorferi'' sensu lato. ''Borrelia'' are microaerophilic and slow-growing—the primary reason for the long delays when diagnosing Lyme disease—and have been found to have greater strain diversity than previously estimated. The strains differ in clinical symptoms and/or presentation as well as geographic distribution. Except for ''Borrelia recurrentis'' (which causes louse-borne relapsing fever and is transmitted by the human body louse), all known species are believed to be transmitted by ticks. ==Species and strains==
Until recently, only three genospecies were thought to cause Lyme disease (borreliosis): ''B. burgdorferi'' sensu stricto (the predominant species in North America, but also present in Europe); ''B. afzelii''; and ''B. garinii'' (both predominant in Eurasia). Totally 10 complete genomes of ''B. burgdorferi'' sensu stricto, ''B. afzelii'' and ''B. garinii'' strains are available on NCBI Genome server at Feb 2013. ''B. burgdorferi'' strain B31 was derived by limited dilutional cloning from the original Lyme-disease tick isolate derived by Alan Barbour.
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