翻訳と辞書 Words near each other ・ M3 Lee ・ M3 Motorsport ・ M3 motorway ・ M3 motorway (Great Britain) ・ M3 motorway (Hungary) ・ M3 motorway (Northern Ireland) ・ M3 motorway (Pakistan) ・ M3 Parkway railway station ・ M197 electric cannon ・ M1975 ・ M198 ・ M198 howitzer ・ M1A1 ・ M1A1 Flamethrower ・ M1C helmet ・ M1G ・ M1NT ・ M1W Heavyweight Championship ・ M2 ・ M2 (Brisbane) ・ M2 (Copenhagen) ・ M2 (game developer) ・ M2 (Istanbul Metro) ・ M2 (Mazda) ・ M2 (missile) ・ M2 (railcar) ・ M2 (Sydney) ・ M2 (TV channel) ・ M2 4.2 inch mortar ・ M2 Bradley Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク M1G ： ウィキペディア英語版 M1G |Section2= |Section3= }} M1G (pyrimido()purin-10(''3H'')-one) is a heterocyclic compound which is a by-product of base excision repair (BER) of a specific type of DNA adduct called M1dG. The M1dG adduct in turn is formed by a condensation reaction between guanosine nucleotides in DNA and either malondialdehyde (propanedial) or acrolein. If not repaired, these adducts are mutagenic and carcinogenic. Malondialdehyde is an end product of lipid peroxidation〔 while acrolein is a result of DNA peroxidation. M1dG is the major endogenous DNA adduct in humans. M1dG adducts have been detected in cell DNA in liver, leucocytes, pancreas and breast in concentrations of 1-120 per 108 nucleotides.〔 Detection and quantification of M1dG adducts in the body as measured by free M1G is a tool for detecting DNA damage that may lead to cancer. Free M1G is also biomarker for oxidative stress.〔 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「M1G」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.