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MAD1L1
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MAD1L1 : ウィキペディア英語版
MAD1L1

Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the ''MAD1L1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8379 )
MAD1L1 is also known as Human Accelerated Region 3. It may therefore have played a key role in differentiating Humans from Apes.
== Function ==

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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