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・ MCM (A Premier Farnell Company)
・ MCM (TV channel)
・ MCM Group
・ MCM London Comic Con
・ MCM pistol
・ MCM Pop
・ MCM-41
・ MCM/70
・ MCM10
・ MCM2
・ MCM3
・ MCM3AP
・ MCM4
・ MCM5
・ MCM6
MCM7
・ MCM8
・ McMackin
・ McMahan
・ McMahan Homestead
・ McMahan Mound Site
・ McMahan's Furniture
・ McMahen
・ McMahon
・ McMahon baronets
・ McMahon Cogeneration Plant
・ McMahon family
・ McMahon Glacier
・ McMahon Government
・ McMahon House


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MCM7 : ウィキペディア英語版
MCM7

DNA replication licensing factor MCM7 is a protein that in humans is encoded by the ''MCM7'' gene.
== Function ==

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4176 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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