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MCPA : ウィキペディア英語版
MCPA

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MCPA (2-methyl-4-chlorophenoxyacetic acid) is a powerful, selective, widely used phenoxy herbicide. The pure compound is a brown-colored powder.
==History==
In 1936 investigations began at ICIs Jealott's Hill research center into the effects of the plant hormones auxins on plant growth looking specifically for a way to kill weeds without harming crops such as corn.〔The Times, 2 July 1954; Imperial Chemical Industries Limited: Display Advertising〕
Synthesis of MCPA was first reported by Synerholme and Zimmerman in 1945 and by Templeman and Foster in 1946. Templeman and Foster were searching for compounds with similar or greater selective activity than 1-naphthaleneacetic acid in inhibiting the growth of weeds while not adversely affecting the growth of cereal grains. They synthesized MCPA from the corresponding phenol by exposing it to chloroacetic acid and dilute base in a straightforward substitution reaction:
:2-methyl-4-chlorophenol + ClCH2CO2H + base → MCPA + base·HCl

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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