翻訳と辞書 Words near each other ・ Merophyas divulsana ・ Merophyas immersana ・ Merophyas leucaniana ・ Merophyas paraloxa ・ Merophyas petrochroa ・ Merophyas scandalota ・ Merophyas siniodes ・ Merophyas tenuifascia ・ Merophyas therina ・ Meropi ・ Meropis ・ Meropis (moth) ・ Meroplankton ・ Meropleon ・ Meropleon diversicolor ・ MEROPS ・ Merops ・ Merops (genus) ・ Merops (mythology) ・ Meroptera ・ Meroptera abditiva ・ Meroptera anaimella ・ Meroptera cviatella ・ Meroptera mirandella ・ Meroptera nevadensis ・ Meroptera pravella ・ Meros ・ Merosaurus ・ Meroscelisus ・ Meroselenidium Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MEROPS ： ウィキペディア英語版 MEROPS MEROPS is an on-line database for peptidases (also known as proteases) and their inhibitors. The classification scheme for peptidases was published by Rawlings & Barrett in 1993,〔Rawlings, N.D. & Barrett, A.J. (1993) Evolutionary families of peptidases. ''Biochem J'' 290, 205-218.〕 and that for protein inhibitors by Rawlings ''et al.'' in 2004.〔Rawlings, N.D., Tolle, D.P. & Barrett, A.J. (2004) Evolutionary families of peptidase inhibitors. ''Biochem J'' 378, 705-716.〕 ==Overview== The classification is based on similarities at the tertiary and primary structural levels. Comparisons are restricted to that part of the sequence directly involved in the reaction, which in the case of a peptidase must include the active site, and for a protein inhibitor the reactive site. The classification is hierarchical: sequences are assembled into families, and families are assembled into clans. A family is assembled around a ''type example'', the sequence of a well-characterized peptidase or inhibitor. All other sequences in the family must be related to the family type example, either directly or through a transitive relationship involving one or more sequences already shown to be family members. Typically, FastA or BlastP are used to establish sequence relationships, with an expect value of 0.001 or lower taken to be statistically significant. A clan is also assembled around a type example, this being the structure of a well-characterized peptidase or inhibitor. A family is included in a clan if the tertiary structure of a family member can be shown to be related to that of the clan type example. Typically, DALI is used to establish clan membership, with a z score of 6.00 standard deviation units or above considered to be statistically significant. For peptidases, other evidence to indicate that families are related when a tertiary structure is absent includes the same order of catalytic residues in the sequences. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MEROPS」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.