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MK-2048
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection. It is superior to the first available integrase inhibitor, raltegravir, in that it inhibits the HIV enzyme integrase 4 times longer. It is being investigated for use as part of pre-exposure prophylaxis (PrEP). 〔Keith Alcorn. (Ralvetgravir shows potential for use as PrEP drug ) AIDSmap.com. 28 April 2009. Accessed 8 Nov 2009.〕 It is being developed by Merck & Co.〔Mark Mascolini. (Merck Offers Unique Perspective on Second-Generation Integrase Inhibitor. ) 10th International Workshop on Clinical Pharmacology of HIV Therapy, April 15–17, 2009, Amsterdam. Accessed 8 Nov 2009.〕 ==References==
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