翻訳と辞書 Words near each other ・ Mkrtich Avetisian ・ Mkrtich Khrimian ・ Mkrtich Mazmanian ・ MKS ・ MKS (Switzerland) ・ MKS Będzin ・ MKS Dąbrowa Górnicza ・ MK Panduranga Setty ・ MK postcode area ・ MK Preshow Shimray ・ MK Publishers ・ MK Sportscars ・ Mk Ultra ・ MK-2048 ・ MK-212 ・ MK-2206 ・ MK-9470 ・ MK-DOS ・ MK-Motorsport ・ MK-Ultra (band) ・ MK-V AR ・ MK1 (disambiguation) ・ MK12 ・ MK14 ・ MK2 ・ MK3 grenade ・ MK4 ・ Mk44 ・ Mk44 Bushmaster II ・ MK484 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MK-2206 ： ウィキペディア英語版 MK-2206 MK-2206 is a drug candidate being investigated to help treat cancer. Its chemical formula is C25H21N5O.〔(MK-2206 dihydrochloride (CAS 1032350-13-2) ) inc structure diagram〕 It acts as an allosteric AKT inhibitor.〔(MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo. Hirai et al. 2010 )〕 It is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3.〔 It is intended to be used with other cancer therapies that advanced tumours may become resistant to.〔 ==Clinical trials== 2011: A phase 1 clinical trial of MK-2206 alone has reported it was well tolerated.〔(First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors. )〕 2014: A phase 1 clinical trial of MK-2206 with a variety of other agents in 72 patients with advanced cancer reported acceptable side-effects.〔(A trial of MK-2206 with chemotherapy or erlotinib for advanced cancer )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MK-2206」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.