翻訳と辞書 Words near each other ・ MLSE ・ MLSSA ・ MLST8 ・ MLSTD2 ・ MLT ・ MLT-3 encoding ・ MLton ・ MLTR (album) ・ Mlečva ・ Mleščevo ・ MLF ・ MLF1 ・ MLF1IP ・ MLG ・ MLH ・ MLH1 ・ MLH3 ・ MLHS ・ MLI ・ MLI-84 ・ MLIA ・ Mlib Tmetuchl ・ Mliba ・ Mlibizi ・ Mlibo Ngewu ・ Mlice-Kostery ・ Mliha ・ Mlik ・ Mlilot ・ Mlilwane Wildlife Sanctuary Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MLH1 ： ウィキペディア英語版 MLH1 MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) is a protein that in humans is encoded by the MLH1 gene located on Chromosome 3. It is a gene commonly associated with hereditary nonpolyposis colorectal cancer. Orthologs of human MLH11 have also been studied in other organisms including mouse and the budding yeast ''Saccharomyces cerevisiae''. == Function == This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the ''E. coli'' DNA mismatch repair gene, mutL, which mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Defects in MLH1 are associated with the microsatellite instability (MSI) observed in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4292 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MLH1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.