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MMP10 : ウィキペディア英語版
MMP10

Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the ''MMP10'' gene.
== Function ==

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4319 )
MMP10 has been linked to cancer stem cell vitality and metastasis 〔http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035040?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+plosone%2FBiochemistry+%28PLoS+ONE+Alerts%3A+Biochemistry%29〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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