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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MODELLER ： ウィキペディア英語版 MODELLER MODELLER is a computer program used in producing homology models of protein tertiary structures as well as quaternary structures (rarer). It implements a technique inspired by nuclear magnetic resonance known as ''satisfaction of spatial restraints'', by which a set of geometrical criteria are used to create a probability density function for the location of each atom in the protein. The method relies on an input sequence alignment between the target amino acid sequence to be modeled and a template protein whose structure has been solved. The program also incorporates limited functionality for ab initio structure prediction of loop regions of proteins, which are often highly variable even among homologous proteins and therefore difficult to predict by homology modeling. MODELLER was originally written and is currently maintained by Andrej Sali at the University of California, San Francisco. Although it is freely available for academic use, graphical user interfaces and commercial versions are distributed by Accelrys. The ModWeb comparative protein structure modeling webserver is based on MODELLER and other tools for automatic protein structure modeling, with an option to deposit the resulting models into ModBase. A freely available GUI to MODELLER called (EasyModeller ) is developed by Kuntal Kumar Bhusan at (University Of Hyderabad,India ). A new version of EasyModeller (EasyModeller 4.0) has been recently released and available for free download for Linux and Windows OS. There is also a simple interface to MODELLER in the program UCSF Chimera. ==See also== *Protein structure prediction software 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MODELLER」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.