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MT-45 (IC-6) is an opioid analgesic drug invented in the 1970s by Dainippon Pharmaceutical Co. It is chemically a 1-substituted-4-(1,2-diphenylethyl)piperazine derivative, which is structurally unrelated to most other opioid drugs. Racemic MT-45 has around 80% the potency of morphine, with almost all opioid activity residing in the (S) enantiomer (the opposite stereochemistry from the related drug lefetamine). It has been used as a lead compound from which a large family of potent opioid drugs〔US Patent 4080453〕 have been developed, including full agonists, partial agonists, and antagonists at the three main opioid receptor subtypes. Recreational use of MT-45 has been associated with hearing loss and unconsciousness. MT-45 became a class A drug in the UK on 11 March 2015 ==See also== * AH-7921 * AD-1211 * Diphenidine * Ephenidine * Fluorolintane * IC-26 * Lanicemine * Lefetamine * Methoxphenidine (MXP) * Remacemide 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「MT-45」の詳細全文を読む スポンサード リンク
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