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Malonate
The malonate or propanedioate ion is CH2(COO)22− (malonic acid minus two hydrogen ions). Malonate compounds include salts and esters of malonic acid, such as *diethyl malonate, (C2H5)2(C3H2O4), *dimethyl malonate, (CH3)2(C3H2O4), *disodium malonate, Na2(C3H2O4). Malonate is a competitive inhibitor of the enzyme succinate dehydrogenase: malonate binds to the active site of the enzyme without reacting, and so competes with succinate, the usual substrate of the enzyme. The observation that malonate is a competitive inhibitor of succinate dehydrogenase was used to deduce the structure of the active site in that enzyme. ==See also==
*Malonic ester synthesis
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Malonate」の詳細全文を読む
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