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Japanese rice fish
The Japanese rice fish (''Oryzias latipes''), also known as the medaka and Japanese killifish, is a member of genus ''Oryzias'' (ricefish), the only genus in the subfamily Oryziinae. This small (up to ) native of East and Mainland Southeast Asia is a common denizen of rice paddies, marshes, ponds, slow-moving streams and tide pools. It is euryhaline, occurring in both brackish and freshwater.〔 It became popular as an aquarium fish because of its hardiness and pleasant coloration: its coloration varies from brown or yellow-gold in the wild to white, creamy yellow, or orange in aquarium-bred individuals. The medaka has been a popular pet since the 17th century in Japan. The female carries her eggs attached between her anal fins. ==Description== ''Oryzias latipes'' is a model organism and is extensively used in many areas of biological research, most notably in toxicology. Medaka have a short gestation period, and are reproductively prolific — characteristics that make them easy to rear in the laboratory. They can withstand cold and can be shipped easily. Nearly all aspects of the life cycle of medaka have been analyzed by researchers including sexual behavior, genetic inheritance of coloration, spawning habits, feeding, pathology, embryological development, ecology, etc. It has relatively small genome (~800 Mb, half the size of the genome of another popular model fish, the zebrafish) as well as a generation time of 7 weeks (rather than 9 weeks for zebrafish) and hardier growth in a broad temperature range (6–40 degrees °C). Transgenic medaka are relatively easy to produce. They have been genetically modified to secrete various human hormones, express promoter sequences from other fish, and to make antimicrobial proteins and a protein that makes the medaka glow fluorescent green. There are also many mutations that show up in medaka at random, for example, a mutant strain that lacks scales, and one with extra-long fins. Haploid embryonic stem cell lines have been established.〔Yi, M., et al. (Generation of medaka fish haploid embryonic stem cells. ) ''Science'' 326(5951), 430-33, 16 October 2009.〕
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